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Osteoporosis Denosumab
Desk job, car, bar
Mechanism: Denosumab is injected every 6 months. After every denosumab injection, the osteoclasts die because of the absence of RANKL. In the time between one injection and the next, osteoclasts are formed from precursors. As a result of accumulation of osteoclast precursors due to blocking of differentiation by denosumab, the osteoclast recovery increases over time.