List of original articles using the micro-CT data in the Data section

  1. F. A. Schulte, F. M. Lambers, G. Kuhn and R. Müller. In vivo micro-computed tomography allows direct three-dimensional quantification of both bone formation and bone resorption parameters using time-lapsed imaging. Bone, Epub 2010 Oct 12, 48:433-442, 2011.
  2. A. J. Wirth, J. Goldhahn, C. Flaig, P. Arbenz, R. Müller and G. H. van Lenthe. Implant stability is affected by local bone microstructural quality. Bone, 49:473-478, 2011.
  3. A. Cohen, D. W. Dempster, R. R. Recker, E. M. Stein, J. M. Lappe, H. Zhou, A. J. Wirth, G. H. van Lenthe, T. Kohler, A. Zwahlen, R. Müller, C. J. Rosen, S. Cremers, T. L. Nickolas, D. J. McMahon, H. Rogers, R. B. Staron, J. LeMaster and E. Shane. Abnormal bone microarchitecture and evidence of osteoblast dysfunction in premenopausal women with idiopathic osteoporosis. J. Clin. Endocr. Metab., 96:3095-3105, 2011.
  4. F. A. Schulte, F. M. Lambers, D. J. Webster, G. Kuhn and R. Müller. In vivo validation of a computational bone adaptation model using open-loop control and time-lapsed micro-computed tomography. Bone, 49:1166-1172, 2011.
  5. R. Voide, P. Schneider, M. Stauber, G. H. van Lenthe, M. Stampanoni and R. Müller. The importance of murine cortical bone microstructure for microcrack initiation and propagation. Bone, 49:1186-1193, 2011.
  6. V. Entezari, V. Vartanians, D. Zurakowski, N. Patel, R. J. Fajardo, R. Müller, B. D. Snyder and A. Nazarian. Further improvements on the factors affecting bone mineral density measured by quantitative micro-computed tomography. Bone, 50:611-618, 2012.
  7. D. Christen, A. Levchuk, S. Schori, P. Schneider, S. K. Boyd and R. Müller. Deformable image registration and 3D strain mapping for the quantitative assessment of cortical bone microdamage. J. Mech. Behav. Biomed. Mater., 8:184-193, 2012.
  8. A. J. Wirth, R. Müller and G. H. van Lenthe. The discrete nature of trabecular bone microarchitecture affects implant stability. J. Biomech., 45:1060-1067, 2012.
  9. F. A. Schulte, A. Zwahlen, F. M. Lambers, G. Kuhn, D. Ruffoni, D. Betts, D. J. Webster and R. Müller. Strain-adaptive in silico modeling of bone adaptation – a computer simulation validated by in vivo micro-computed tomography data. Bone, 52:485-492, 2013.
  10. S. E. Basler, J. Traxler, R. Müller and G. H. van Lenthe. Peri-implant bone microstructure determines dynamic implant cut-out. Med. Eng. Phys., 35:1442-1449, 2013.
  11. L. Nebuloni, G. A. Kuhn and R. Müller. A comparative analysis of water-soluble and blood-pool contrast agents for vascular imaging with micro-CT. Acad. Radiol., 20:1247-1255, 2013
  12. B. W. Thimm, O. Wechsler, M. Bohner, R. Müller and S. Hofmann. In vitro monitoring of ceramic scaffold mineralization: comparison between histological and micro-computed tomographical analysis. Ann. Biomed. Eng., 41:2666-2675, 2013
  13. D. Christen, L. J. Melton 3rd, A. Zwahlen, S. Amin, S. Khosla and R. Müller. Improved fracture risk assessment based on nonlinear micro-finite element simulations from HRpQCT images at the distal radius. J. Bone Miner. Res., 28:2601-2608, 2013
  14. D. Christen, A. Zwahlen and R. Müller. Reproducibility for linear and nonlinear micro-finite element simulations with density derived material properties of the human radius. J. Mech. Behav. Biomed. Mater., 29:500-507, 2014.
  15. L. Nebuloni, G. A. Kuhn, J. Vogel and R. Müller. A novel in vivo vascular imaging approach for hierarchical quantification of vasculature using contrast enhanced micro-computed tomography. PLoS One, 9(1):e86562, 2014.
  16. F. A. Schulte, F. M. Lambers, T. L. Mueller, M. Stauber and R. Müller. Image interpolation allows accurate quantitative bone morphometry in registered micro-computed tomography scans. Comput. Methods Biomech. Biomed. Engin., Epub 2012 Jun 29, 17:539-548, 2014.
  17. O. F. Vila, M. M. Martino, L. Nebuloni, G. Kuhn, S. Pérez-Amodio, R. Müller, J. A. Hubbell, N. Rubio and J. Blanco. Bioluminescent and micro-computed tomography imaging of bone repair induced by fibrin-binding growth factors. Acta Biomater., 10:4377-4389, 2014
  18. F. Donaldson, D. Ruffoni, P. Schneider, A. Levchuk, A. Zwahlen, P. Pankaj and R. Müller. Modeling microdamage behavior of cortical bone. Biomech. Model. Mechanobiol., 13:1227-1242, 2014.
  19. F. M. Lambers, G. Kuhn, C. Weigt, K. M. Koch, F. A. Schulte and R. Müller. Bone adaptation to cyclic loading in murine caudal vertebrae is maintained with age and directly correlated to the local micromechanical environment. J. Biomech., 48:1179-1187, 2015.
  20. K. S. Mader, L. R. Donahue, R. Müller and M. Stampanoni. High-throughput phenotyping and genetic linkage of cortical bone microstructure in the mouse. BMC Genomics, 16:493, 2015
  21. S. D. Badilatti, P. Christen, A. Levchuk, J. H. Marangalou, B. van Rietbergen, I. Parkinson and R. Müller. Large-scale microstructural simulation of load-adaptive bone remodeling in whole human vertebrae. Biomech. Model. Mechanobiol., 15:83-95, 2016
  22. M. Georgiadis, M. Guizar-Sicairos, O. Gschwend, P. Hangartner, O. Bunk, R. Müller and Philipp Schneider. Ultrastructure organization of human trabeculae assessed by 3D sSAXS and relation to bone microarchitecture. PLoS One, 11(8):e0159838, 2016
  23. S. D. Badilatti, P. Christen, I. Parkinson and R. Müller. Load-adaptive bone remodeling simulations reveal osteoporotic microstructural and mechanical changes in whole human vertebrae. J. Biomech., 49:3770-3779, 2016.
  24. M. Casanova, A. Balmelli, D. Carnelli, D. Courty, P. Schneider and R. Müller. Nanoindentation analysis of the micromechanical anisotropy in mouse cortical bone. R. Soc. Open Sci., 4:160971, 2017
  25. Z. Li, G. Kuhn, M. Schirmer, R. Müller and D. Ruffoni. Impaired bone formation in ovariectomized mice reduces implant integration as indicated by time-lapsed in vivo micro-computed tomography. PLoS One, 12(9):e0184835, 2017.
  26. A. Levchuk, P. Schneider, M. Meier, P. Vogel, F. Donaldson and R. Müller. An automated step-wise micro-compression device for 3D dynamic image-guided failure assessment of bone tissue on a microstructural level using time-lapsed tomography. Front. Mater., 5:32, 2018.
  27. E. Wehrle, D. C. Tourolle né Betts, G. A. Kuhn, A. C. Scheuren, S. Hofmann and R. Müller. Evaluation of longitudinal time-lapsed in vivo micro-CT for monitoring fracture healing in mouse femur defect models. Sci. Rep., 9:17445, 2019.
  28. A. C. Scheuren, G. A. Kuhn and R. Müller. Effects of long-term in vivo micro-CT imaging on hallmarks of osteopenia and frailty in aging mice. PLoS One, 15:e0239534, 2020.
  29. M. Walle, F. C. Marques, N. Ohs, M. Blauth, R. Müller and C. J. Collins. Bone mechanoregulation allows subject-specific load estimation based on time-lapsed micro-CT and HR-pQCT in vivo. Front. Bioeng. Biotechnol., 9:677985, 2021.
  30. E. Goff, F. Buccino, C. Bregoli, J. P. McKinley, B. Aeppli, R. R. Recker, E. Shane, A. Cohen, G. Kuhn and R. Müller. Large-scale quantification of human osteocyte lacunar morphological biomarkers as assessed by ultra-high-resolution desktop micro-computed tomography. Bone, 152:116094, 2021
  31. G. R. Paul, P. Vallaster, M. Rüegg, A. C. Scheuren, D. C. Tourolle, G. A. Kuhn, E. Wehrle and R. Müller. Tissue level regeneration and remodelling dynamics are driven by mechanical stimuli in the microenvironment in a post-bridging loaded femur defect healing model in mice. Front. Cell Dev. Biol., in press, 2022.
  32. N. Ohs, D. C. Tourolle né Betts, P. R. Atkins, S. Sebastian, B. van Rietbergen, M. Blauth, P. Christen and R. Müller. Upscaling of in vivo HR-pQCT images enables accurate simulations of human microstructural bone adaptation. In preparation, preprint available on bioRxiv, 2022.